Question:
gs <he…@rest.net
wrote in message
news:182863D9227BA940.C5295BA6B4991D89.3AD99ED25F4624D7@lp.airnews.net…
All I can say is my Mom died from undiagnosed thyroid problem.
How did her doctors overlook this. Thyroid disease is obviously a very common condition seen in doctor’s offices. It ’s signs are pretty obvious. How does it cause death? J It is a very – Hide quoted text — Show quoted text -
real health concern. Especially for older women. I think people should read studies, and then question their doctors. It is a very REAL problem. Now this article particularly interests me because of my co-worker who’s taking Synthroid and has now been given Evista to prevent the Synthroid from giving her osteoporosis. I asked her why she was taking Synthroid in the first place, and she
said
she’d had no symptoms, but was put on it after a blood test showed she
was
mildly hypothyroid. She said the doctor told her that the thyroid gland "just deteriorates with age." (She was in her 40s at the time, is now 52.) I asked her why she was given Evista rather than Fosamax, and she said
"My
doctor said Evista is better than Fosamax because it also lowers your
bad
cholesterol." When I asked her that question, I hadn’t read this
article
yet and didn’t realize that the Synthroid itself is supposed to be lowering her cholesterol. But I checked the PDR. I found that Evista increases the risk of
ovarian
cancer (in rats, no data on humans yet) and the risk of abnormal blood clot formation. Fosamax doesn’t have any such dangerous risks, although the way you have to *take* Fosamax is a big pain in the butt. I find this all very interesting. Eva Sounds like your friend needs to get active in her healthcare. Symptoms
of
thyroid disease often go unnoticed because they are so symptoms of various other conditions….perimenopause and menopause for example. Maybe you should *encourage* your friend to question her doctor and the choice of medication. gs
Response:
With this drug-company funded study, again I ask, "what goes wrong with so many US thyroids, and why mostly women’s thyroids? Is a drug company funded study the best source of information on this topic? Is there an inherent conflict of interests when you read the full details of this study and not just the sound-byte conclusions? J gs <he…@rest.net
wrote in message
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<droz…@home.com wrote in message news:38d9b40c.37243615@news… On 23 Mar 2000 05:26:57 GMT, mpitc2…@aol.comnospam (MPitc2000) wrote: New Study Shows Twice as Many Americans May Suffer from Undiagnosed Thyroid Disease I don’t think that anyone on asm has ever said that undiagnosed thryroid disease was not a problem. It has been asked on asm what is going wrong with so many *women’s*
thyroid,
that Syntroid is the number two drug. Largest-Ever Prevalence Study Links Mildest Forms of Hypothyroidism to Increases in Cholesterol; Exposes Need for More Widespread Thyroid Testing DENVER, Feb. 27 /PRNewswire/ — The largest study to date evaluating
the
prevalence of thyroid disease indicates there may be more than 13
million
Americans who are unaware they have a thyroid condition even though the disease may be impacting their short- and long-term health. For the original study article in the Feb 28 2000 Archives of Internal Medicine online see: http://archinte.ama-assn.org/issues/v160n4/full/ioi90027.html The Colorado Thyroid Disease Prevalence Study Gay J. Canaris [ et al ] [ small quote ] Results from this study also highlighted the large number of patients taking thyroid hormones who were not in the therapeutic range. Clinicians may therefore consider monitoring patients on thyroid replacement more frequently. 40% of those on thyroid medications in fact. Why?. Overtreatment could be one part of this and that is what all the commotion was about on asm recently. Kathryn droz…@home.com It is saying that patients on thyroid medication need to be monitored closer. Too many are given the medication, and doctors think it will magically bring them to the proper level. Therefore, the study is pointing out the need to monitor these patients closely, too much or too little medication is a problem. gs
Response:
Eva D. Struction <EvaDSt…@aol.com
wrote in message
news:QInC4.16697$
Knoll Now this article particularly interests me because
of my co-worker who’s
taking Synthroid and has now been given Evista to prevent the Synthroid
from
giving her osteoporosis.
I hate seeing this as a trend t ocover up the trail of the misuse of thyroid prescriptions.. Always best at this time to go back and revisit the efficacy of the first diagnosis and the first medication before starting this drug-layering process; when one drug gets added to deal with the side-effects caused by the first drug. This creates this endless spiral and one gives over their bodies and often their lives to chasing a drug down-fall that can be often far worse than the underlying condition that started the whole thing. My constant advice, look into the cause of conditions, evaluate non-drug alternatives to affect the cause, before embarking on drug dead-ends treating only the symptoms. Evista in cahoots with all the over-prescribing of Synthroid is a scary site to behold. The Evista will now cause hot flashes, and that will lead to HRT prescriptions, which will lead to more breast cancers which will lead to more Tamoxifin prescriptions, which will increass blood pressure and raise cholesterol which will lead to drugs for HBP and lowering cholesterol, and drugs to counteract the progesterone induced depressions, and possibly drugs to control the migraines……….Stop the Insanity! Enough already. Re-investigate the need for the first drug. See what other information has been learned about the underlying condition. Read the drug label, particularly for Synthroid to see if you are really using it for authorized conditions, and proceed very very carefully when starting this drug layering downfall. J – Hide quoted text — Show quoted text -
I asked her why she was taking Synthroid in the first place, and she said she’d had no symptoms, but was put on it after a blood test showed she was mildly hypothyroid. She said the doctor told her that the thyroid gland "just deteriorates with age." (She was in her 40s at the time, is now
52.)
I asked her why she was given Evista rather than Fosamax, and she said "My doctor said Evista is better than Fosamax because it also lowers your bad cholesterol." When I asked her that question, I hadn’t read this article yet and didn’t realize that the Synthroid itself is supposed to be
lowering
her cholesterol. But I checked the PDR. I found that Evista increases the risk of ovarian cancer (in rats, no data on humans yet) and the risk of abnormal blood
clot
formation. Fosamax doesn’t have any such dangerous risks, although the
way
you have to *take* Fosamax is a big pain in the butt. I find this all very interesting. Eva
Response:
On 23 Mar 2000 05:26:57 GMT, mpitc2…@aol.comnospam (MPitc2000) wrote:
Average total cholesterol levels for patients with overt hypothyroidism were 251 mg/dL and the average total cholesterol levels for subclinical hypothyroid patients were 224 mg/dL — both above 200 mg/dL, the marker used to indicate elevated cholesterol levels that warrant medical attention. Because the connection between hypothyroidism and cholesterol is so clear, the National Cholesterol Education Program and the U.S. Food and Drug Administration recommend thyroid testing in patients with high cholesterol levels.
This connection may be well known among people who regularly deal with thyroid problems, but I think it is pretty much unsuspected by the public at large. <snip
"Thyroid symptoms are so common and are often mistaken for signs of aging, menopause, depression or stress," said Gay Canaris, MD, assistant professor of internal medicine, University of Nebraska Medical Center. "Since we can’t rely upon reported symptoms alone to detect disease, we as physicians should be conducting more thyroid testing."
<snip
Serum TSH concentrations were measured by third-generation immunochemiluminescent assay. Normal range was a TSH level between 0.3 and 5.1 mIU/L, subclinical hypothyroidism was characterized by an elevated TSH level (greater than 5.1 mIU/L) and a normal T4, and overt hypothyroidism was evaluated as an elevated TSH level (greater than 10.0 mIU/L) and a decreased T4.
Some people still argue that subclinical hypothyroidism does not exist.
Response:
On Thu, 23 Mar 2000 06:39:25 GMT, droz…@home.com wrote:
For the original study article in the Feb 28 2000 Archives of Internal Medicine online see: http://archinte.ama-assn.org/issues/v160n4/full/ioi90027.html Results from this study also highlighted the large number of patients taking thyroid hormones who were not in the therapeutic range. Clinicians may therefore consider monitoring patients on thyroid replacement more frequently. 40% of those on thyroid medications in fact. Why?. Overtreatment could be one part of this and that is what all the commotion was about on asm recently.
Did you read the data in Table 2 of the report? I’ll reproduce the relevant part: Subjects taking thyroid medication (n=1525) Euthyroid 916 (60.1%) Hypothyroid 11 (0.7%) Subclinical hypothyroid 269 (17.6) Hyperthyroid 13 (0.9) Subclinical hyperthyroid 316 (20.7) Lumping together clinical and subclinical cases, 18% had too little medication and 22% had too much. The majority of these cases were subclinical. So the recommendation means exactly what it says: when a patient is already on thyroid medication, that patient should probably be monitored more carefully than is present practice. It does NOT mean that medication is being given unnecessarily, which is what you are implying.
Response:
Thanks for this post, tishy I get the impression that many still do not get how much for-profit money and advertising has entered into the health care field. This has been steady since the introduction of Tagamet, over 15 years ago. The entire field is riddled with abuse today. And this is a sorry state of affairs. The only good thing I see, is that it is temporary and that more accesss to better education will bring us the best of all possible worlds in health care when these issues all settle out. But this will take a decade or so. Stay well until then. J <ti…@cheerful.com
wrote in message
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On Fri, 24 Mar 2000 03:56:47 GMT, "Joan Livingston" <joan.livingst…@gte.net wrote: Or the real black-helicopter speculation is that this whole thyroid-osteo threat has been concocted by Evista to boost their decidely lagging sales Today I visited a large book store and there discovered in the "mindbenders" section of the current magazine "Adbusters" (which is a Canadian publication but available in the US at Borders etc) a two page feature dealing with the presentation of raloxifene (Evista). On the left hand page there is a reproduction of an article from the New York times – with suitably highlighted sections. On the right page there is commentary on the highlighted bits which critiques the pronounced positive bias of the article. I was intrigued to find that the content was so very similar to past asm posts and links available for the the raloxifene section of M&B that no regular reader here would learn anything new from it. Moving from the magazine section to the bookshelves I came upon a new (to me) book on natural progesterone. In the chapter on "progesterone for men" I was informed that the falling levels of testosterone in men and the resultant shift in balance with estrogen leading to the development of fatty breasts as they age may be an indication of "estrogen dominance" so…. Need I say more? In the Bargain Books section the 1998 book (also new to me) entitled "Menopause and Madness" originally priced at $C34.95 was selling (or offered for sale at least) at the paltry price of C$4.95 despite promising to tell what it means for all women that one woman in particular had been saved from madness by estrogen replacement. Tishy
Response:
Talk to some people in the grad schools at research institutions who laugh at the protocols they are often asked to "test". The answers are foregone conclusions, even before the studies start. It should have been disclosed up front that Synthroid was paying for that thyroid "study" but it was not. It took a bit of time to track Knoll Laboratories to their product Syntroid. J gs <he…@rest.net
wrote in message
news:767935F04FF740AC.1CF9F70C65070528.93213659934E9F27@lp.airnews.net… – Hide quoted text — Show quoted text -> "Joan Livingston" <joan.livingst…@gte.net
wrote in message
> news:%tBC4.1382$QJ3.238875@dfiatx1-snr1.gtei.net… > > You are right, this was not the most reliable of studies as the study > group > > were people attending a "health fair". And since the study was funded by > the > > makers of Synthroid, who knows what else they learned in their "study" > that > > they did not report. This collection of subjective data about a drug that > is > > paying for the information collection and is doing the compilation under > > unknown directives is as you say, not the most reliable of studies. > > And this is why it is so helpful to discuss all the issues of cited > studies > > so we can get beyond sound-byte "conclusions." > > J > I wasn’t talking about the fact it was funded by the drug company. It has > been mentioned before, but drug companies fund quite a few things. Just > because money is given, doesn’t always mean it is a flawed study. gs > > gs <he…@rest.net
wrote in message
news:B2144DFFFCA3DC3B.A0B62EDA96AF5E25.AB0595D1362AF9C1@lp.airnews.net… – Hide quoted text — Show quoted text -> > > "Joan Livingston" <joan.livingst…@gte.net
wrote in message
> > > news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… > > > > <droz…@home.com> wrote in message news:38da72a7.5017620@news… > > > > > On Thu, 23 Mar 2000 12:21:58 -0500, Robert Ames > <am…@bellsouth.net> > > > > > wrote: > > > > > >. It does NOT > > > > > >mean that medication is being given unnecessarily, which is what > you > > > > > >are implying. > > > > > Not just implying, the article said: > > > > > >These data show that there is an excess of patients who are not > > > > > > in the normal range of thyroid function. Such patients may be at > > risk > > > > > >for organic consequences of overtreatment or undertreatment or (in
the case of those with suppressed TSH levels) may be taking thyroid hormones for reasons other than replacement. Tell me what are these **necessary** reasons for taking thyroid hormones other than as replacement? Feeling good? Weight loss? Or what the doctor teaching a course said about giving out thryoid medications is that they were used as "get out of my office" prescriptions. J Kathryn droz…@home.com If a doctor prescribes a drug, such as synthroid, as a *get out of my office*, or a *feel good* , medicine, that is malpractice. In my experience with doctors, they rarely want to prescribe anything, except antidepressants. The study only has the one sentence talking about taking thyroid medication for reasons other than replacement. It isn’t mentioned anywhere else. This is a study based on people filling out a questionnaire. Not the most reliable of studies. I would like to know for what other reasons someone would take thyroid. Other than…to feel good. I was disappointed that it didn’t mention other reasons. gs
Response:
You are right, this was not the most reliable of studies as the study group were people attending a "health fair". And since the study was funded by the makers of Synthroid, who knows what else they learned in their "study" that they did not report. This collection of subjective data about a drug that is paying for the information collection and is doing the compilation under unknown directives is as you say, not the most reliable of studies. And this is why it is so helpful to discuss all the issues of cited studies so we can get beyond sound-byte "conclusions." J gs <he…@rest.net
wrote in message
news:B2144DFFFCA3DC3B.A0B62EDA96AF5E25.AB0595D1362AF9C1@lp.airnews.net… – Hide quoted text — Show quoted text -> "Joan Livingston" <joan.livingst…@gte.net
wrote in message
> news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… > > <droz…@home.com> wrote in message news:38da72a7.5017620@news… > > > On Thu, 23 Mar 2000 12:21:58 -0500, Robert Ames <am…@bellsouth.net> > > > wrote: > > > >. It does NOT > > > >mean that medication is being given unnecessarily, which is what you > > > >are implying. > > > Not just implying, the article said: > > > >These data show that there is an excess of patients who are not > > > > in the normal range of thyroid function. Such patients may be at risk
for organic consequences of overtreatment or undertreatment or (in the case of those with suppressed TSH levels) may be taking thyroid hormones for reasons other than replacement. Tell me what are these **necessary** reasons for taking thyroid hormones other than as replacement? Feeling good? Weight loss? Or what the doctor teaching a course said about giving out thryoid medications is that they were used as "get out of my office" prescriptions. J Kathryn droz…@home.com If a doctor prescribes a drug, such as synthroid, as a *get out of my office*, or a *feel good* , medicine, that is malpractice. In my
experience
with doctors, they rarely want to prescribe anything, except antidepressants. The study only has the one sentence talking about taking thyroid
medication
for reasons other than replacement. It isn’t mentioned anywhere else.
This
is a study based on people filling out a questionnaire. Not the most reliable of studies. I would like to know for what other reasons someone would take thyroid. Other than…to feel good. I was disappointed that it didn’t mention other reasons. gs
Response:
gs <he…@rest.net
wrote in message
news:F69EBED401586314.27E9AE397520BC7C.6D45FD77ECF4EE3C@lp.airnews.net… > "> "~ Windsong ~" <Fishh…@hotcom.net
wrote in message
> > news:2RyC4.3247$Og6.705832@tw12.nn.bcandid.com… > > > Joan Livingston <joan.livingst…@gte.net
wrote in message
> > > news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… > > > > Or what the doctor teaching a course said about giving out thryoid > > > > medications is that they were used as "get out of my office" > > > prescriptions. > It makes me wonder about the *credibility* of this doctor. What type of > class was he teaching? gs
I applauded his candor. He was a Prof of Clinical Medicine at UCLA Medical School and it was a CEU course called "Calm Before the Storm" dealing with diagnostic trees to help determine what initial symptoms may mean. He was the one who issued the warning (as has been cited to this newsgroup) about the over use of thyroid medications and the threat of this being an osteoporosis-cofactor. It was in response to a question from the audience about some reasons for thyroid medications that he offered this insight about (I gather in the trade) it being used as a "get out of my office" prescription. If one knows medical professionals, this is not an unheard of phenomena. Don’t be too shocked to hear this. Like HRT, thyroid medications have been given for everything from "corns to unhappy marriages." This is how -some- doctors see both drugs and patients. Some patients with collections of symptoms which defy medical common sense can demand the doctor "do something", so he/she hands out what he/she thinks is a benign drug of little consequence. A placebo naturally would be a better choice, but for a long time "hypo-thyroid" was the disease du jour, and the prescriptions got written. Too many people still insist their weight problems are "thyroid problems" and hence this desire for a prescription for those resistent to the exploration of mind/body over-eating issues. I don’t hear "hypo-thyroid" being talked about as much as it once was a while back (in the US), but those prescriptions probably just kept getting renewed and now comes the morbid harvest of the osteoporosis threat. So the campaign from the medical profession has been to try and get women off …until now hearing about putting them on a second drug ..Evista….instead to try and make up for the first level of iatrogenic drug abuse. Or the real black-helicopter speculation is that this whole thyroid-osteo threat has been concocted by Evista to boost their decidely lagging sales …..and since Evista causes hot flashes …enter our good friends W/A with their lagging Premarin sales …….well, you know the picture….. Final analysis, no the guy was not a quack ….he was a truth teller and we need to encourage more of that in medicine. After all no one seems to know why really so many USA thyroid glands have gone so bad to make Synthroid the 2nd leading selling US drug. Maybe, just maybe it was bad prescribing protocol …and women insisting they had "hypothyroid" weight problems……maybe? J – Hide quoted text — Show quoted text -
So we’ll now assume all Dr’s are like that dud? — Carol… Q. What do they call "Hee Haw" in Tennessee? A. A documentary. ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~
Response:
"Joan Livingston" <joan.livingst…@gte.net
wrote in message
news:%tBC4.1382$QJ3.238875@dfiatx1-snr1.gtei.net… – Hide quoted text — Show quoted text -
You are right, this was not the most reliable of studies as the study
group
were people attending a "health fair". And since the study was funded by
the
makers of Synthroid, who knows what else they learned in their "study"
that
they did not report. This collection of subjective data about a drug that
is
paying for the information collection and is doing the compilation under unknown directives is as you say, not the most reliable of studies. And this is why it is so helpful to discuss all the issues of cited
studies
so we can get beyond sound-byte "conclusions." J
I wasn’t talking about the fact it was funded by the drug company. It has been mentioned before, but drug companies fund quite a few things. Just because money is given, doesn’t always mean it is a flawed study. gs > gs <he…@rest.net
wrote in message
> news:B2144DFFFCA3DC3B.A0B62EDA96AF5E25.AB0595D1362AF9C1@lp.airnews.net… > > "Joan Livingston" <joan.livingst…@gte.net
wrote in message
> > news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… > > > <droz…@home.com> wrote in message news:38da72a7.5017620@news… > > > > On Thu, 23 Mar 2000 12:21:58 -0500, Robert Ames
<am…@bellsouth.net
– Hide quoted text — Show quoted text -
wrote: . It does NOT mean that medication is being given unnecessarily, which is what
you
are implying. Not just implying, the article said: These data show that there is an excess of patients who are not in the normal range of thyroid function. Such patients may be at risk for organic consequences of overtreatment or undertreatment or (in the case of those with suppressed TSH levels) may be taking
thyroid
hormones for reasons other than replacement. Tell me what are these **necessary** reasons for taking thyroid hormones other than as replacement? Feeling good? Weight loss? Or what the doctor teaching a course said about giving out thryoid medications is that they were used as "get out of my office" prescriptions. J Kathryn droz…@home.com If a doctor prescribes a drug, such as synthroid, as a *get out of my office*, or a *feel good* , medicine, that is malpractice. In my experience with doctors, they rarely want to prescribe anything, except antidepressants. The study only has the one sentence talking about taking thyroid medication for reasons other than replacement. It isn’t mentioned anywhere else. This is a study based on people filling out a questionnaire. Not the most reliable of studies. I would like to know for what other reasons
someone
would take thyroid. Other than…to feel good. I was disappointed that
it
didn’t mention other reasons. gs
Response:
"Joan Livingston" <joan.livingst…@gte.net
wrote in message
news:3IBC4.1392$QJ3.243178@dfiatx1-snr1.gtei.net… – Hide quoted text — Show quoted text -> gs <he…@rest.net
wrote in message
> news:F69EBED401586314.27E9AE397520BC7C.6D45FD77ECF4EE3C@lp.airnews.net… > > "> "~ Windsong ~" <Fishh…@hotcom.net
wrote in message
> > > news:2RyC4.3247$Og6.705832@tw12.nn.bcandid.com… > > > > Joan Livingston <joan.livingst…@gte.net
wrote in message
> > > > news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… > > > > > Or what the doctor teaching a course said about giving out thryoid
medications is that they were used as "get out of my office" prescriptions. It makes me wonder about the *credibility* of this doctor. What type of class was he teaching? gs I applauded his candor. He was a Prof of Clinical Medicine at UCLA
Medical
School and it was a CEU course called "Calm Before the Storm" dealing with diagnostic trees to help determine what initial symptoms may mean. He was the one who issued the warning (as has been cited to this
newsgroup)
about the over use of thyroid medications and the threat of this being an osteoporosis-cofactor. It was in response to a question from the audience about some reasons for thyroid medications that he offered this insight about (I gather in the trade) it being used as a "get out of my office" prescription. If one knows medical professionals, this is not an unheard of phenomena. Don’t be too shocked to hear this. Like HRT, thyroid
medications
have been given for everything from "corns to unhappy marriages." This is how -some- doctors see both drugs and patients. Some patients with collections of symptoms which defy medical common sense can demand the doctor "do something", so he/she hands out what he/she thinks is a benign drug of little consequence. A placebo naturally would be a better choice, but for a long time "hypo-thyroid" was the disease du jour, and the prescriptions got written. Too many people still insist their weight problems are "thyroid problems" and hence this desire for a prescription
for
those resistent to the exploration of mind/body over-eating issues. I don’t hear "hypo-thyroid" being talked about as much as it once was a while back (in the US), but those prescriptions probably just kept getting renewed and now comes the morbid harvest of the osteoporosis threat. So the campaign from the medical profession has been to try and get
women
off …until now hearing about putting them on a second drug ..Evista….instead to try and make up for the first level of iatrogenic drug abuse. Or the real black-helicopter speculation is that this whole thyroid-osteo threat has been concocted by Evista to boost their decidely lagging sales …..and since Evista causes hot flashes …enter our good friends W/A with their lagging Premarin sales …….well, you know the picture….. Final analysis, no the guy was not a quack ….he was a truth teller and
we
need to encourage more of that in medicine. After all no one seems to know why really so many USA thyroid glands have gone so bad to make Synthroid
the
2nd leading selling US drug. Maybe, just maybe it was bad prescribing protocol …and women insisting they had "hypothyroid" weight problems……maybe? J
Just because some *quacks* decide that thyroid medication is just what someone needed, doesn’t mean it is being over prescribed as a whole. Anyone that would prescribe thyroid medication, or any other medication, just to please a patient, is a QUACK! You and I seem to run into different types of doctors. I have had more problems with dentists, than I have had with doctors. It just amazes me how much more *you* know than the professionals. Everything comes back to hormones, what a vicious circle. How come no one else figures this out? gs – Hide quoted text — Show quoted text -
So we’ll now assume all Dr’s are like that dud? — Carol… Q. What do they call "Hee Haw" in Tennessee? A. A documentary. ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~
Response:
<droz…@home.com
wrote in message news:38d9b40c.37243615@news… On 23 Mar 2000 05:26:57 GMT, mpitc2…@aol.comnospam (MPitc2000) wrote: New Study Shows Twice as Many Americans May Suffer from Undiagnosed
Thyroid
Disease I don’t think that anyone on asm has ever said that undiagnosed thryroid disease was not a problem.
It has been asked on asm what is going wrong with so many *women’s* thyroid, that Syntroid is the number two drug. – Hide quoted text — Show quoted text -
Largest-Ever Prevalence Study Links Mildest Forms of Hypothyroidism to Increases in Cholesterol; Exposes Need for More Widespread Thyroid
Testing
DENVER, Feb. 27 /PRNewswire/ — The largest study to date evaluating the prevalence of thyroid disease indicates there may be more than 13 million Americans who are unaware they have a thyroid condition even though the
disease
may be impacting their short- and long-term health. For the original study article in the Feb 28 2000 Archives of Internal Medicine online see: http://archinte.ama-assn.org/issues/v160n4/full/ioi90027.html The Colorado Thyroid Disease Prevalence Study Gay J. Canaris [ et al ] [ small quote ] Results from this study also highlighted the large number of patients taking thyroid hormones who were not in the therapeutic range. Clinicians may therefore consider monitoring patients on thyroid replacement more frequently. 40% of those on thyroid medications in fact. Why?. Overtreatment could be one part of this and that is what all the commotion was about on asm recently. Kathryn droz…@home.com
It is saying that patients on thyroid medication need to be monitored closer. Too many are given the medication, and doctors think it will magically bring them to the proper level. Therefore, the study is pointing out the need to monitor these patients closely, too much or too little medication is a problem. gs
Response:
I don’t know the reason behind it, but women are much more likely than men to have auto-immune disorders, one of which is a thyroid (either hypo or hyper) condition. Auto-immune disorders also tend to show up in clumps. For example, I am hyperthyroid (although am okay on Tapazole) & have Raynaud’s Disease; also have many allergies, which is also considered an auto-immune disorder. Cathy Joan Livingston <joan.livingst…@gte.net
wrote in message
news:8OqC4.499$8S6.36818@paloalto-snr1.gtei.net… – Hide quoted text — Show quoted text -
With this drug-company funded study, again I ask, "what goes wrong with so many US thyroids, and why mostly women’s thyroids? Is a drug company funded study the best source of information on this
topic?
Is there an inherent conflict of interests when you read the full details
of > this study and not just the sound-byte conclusions? > J > gs <he…@rest.net
wrote in message
> news:F8283FE2FB053104.05354E0CC086F810.E9D6F48694D58EFE@lp.airnews.net… > > <droz…@home.com> wrote in message news:38d9b40c.37243615@news… > > > On 23 Mar 2000 05:26:57 GMT, mpitc2…@aol.comnospam (MPitc2000) > > > wrote: > > > >New Study Shows Twice as Many Americans May Suffer from Undiagnosed > > Thyroid > > > >Disease > > > I don’t think that anyone on asm has ever said that undiagnosed > > > thryroid disease was not a problem. > > It has been asked on asm what is going wrong with so many *women’s* > thyroid, > > that Syntroid is the number two drug. > > > >Largest-Ever Prevalence Study Links Mildest Forms of Hypothyroidism to
Increases in Cholesterol; Exposes Need for More Widespread Thyroid Testing DENVER, Feb. 27 /PRNewswire/ — The largest study to date evaluating the prevalence of thyroid disease indicates there may be more than 13 million Americans who are unaware they have a thyroid condition even though
the
disease may be impacting their short- and long-term health. For the original study article in the Feb 28 2000 Archives of Internal Medicine online see: http://archinte.ama-assn.org/issues/v160n4/full/ioi90027.html The Colorado Thyroid Disease Prevalence Study Gay J. Canaris [ et al ] [ small quote ] Results from this study also highlighted the large number of patients taking thyroid hormones who were not in the therapeutic range. Clinicians may therefore consider monitoring patients on thyroid replacement more frequently. 40% of those on thyroid medications in fact. Why?. Overtreatment could be one part of this and that is what all the commotion was about on asm recently. Kathryn droz…@home.com It is saying that patients on thyroid medication need to be monitored closer. Too many are given the medication, and doctors think it will magically bring them to the proper level. Therefore, the study is
pointing
out the need to monitor these patients closely, too much or too little medication is a problem. gs
Response:
"
"~ Windsong ~" <Fishh…@hotcom.net wrote in message news:2RyC4.3247$Og6.705832@tw12.nn.bcandid.com… Joan Livingston <joan.livingst…@gte.net wrote in message news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… Or what the doctor teaching a course said about giving out thryoid medications is that they were used as "get out of my office" prescriptions.
It makes me wonder about the *credibility* of this doctor. What type of class was he teaching? gs – Hide quoted text — Show quoted text -
So we’ll now assume all Dr’s are like that dud? — Carol… Q. What do they call "Hee Haw" in Tennessee? A. A documentary. ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~
Response:
"~ Windsong ~" <Fishh…@hotcom.net
wrote in message
news:2RyC4.3247$Og6.705832@tw12.nn.bcandid.com… > Joan Livingston <joan.livingst…@gte.net
wrote in message
> news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… > > Or what the doctor teaching a course said about giving out thryoid > > medications is that they were used as "get out of my office" > prescriptions. > ============ > So we’ll now assume all Dr’s are like that dud? > — > Carol… > Q. What do they call "Hee Haw" in Tennessee? > A. A documentary. > ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~ @{ ~~~
Actually, this doctor was an ass! That is a stupid statement for anyone to make, let alone a doctor. Showed his true colors! Sounds like he just wants to make money. gs
Response:
Unfortunately, this is the way older adult’s healthcare is managed. That is another area that has been lacking in health studies, older adults. Everytime there is a new symptom, or illness, a new pill is added. I’ve never understood how doctors can’t figure out that many pills can’t possibly be good for anyone. Think of the possibility of side effects! Gail, I am sorry about your loss. gs "Gail Gillespie" <gail…@mindspring.com
wrote in message
news:38DA53A9.1A5D@mindspring.com… – Hide quoted text — Show quoted text -
Joan’s speculative scenario about drug-layering really rang a bell with me! At the time of my mother’s death from breast cancer last month she was taking 21 different medications (including synthroid, by the way…her thyroid had been destroyed by radiation about 11 years ago.) Her breast cancer had been diagnosed in 1972 and since then she was in and out of the hospital for chemo, radiation and reconstructive surgeries countless times. (Actually, I am going amuse myself by counting some of these things- creating a chronology of her trials…I just received all her medical records and her calendars back to the mid-70s.) Each surgery or treatment generated a host of auxillary drugs to deal with the myriad symptoms created by the treatment or surgery, increasing the drugs geometrically. She rarely left a doctor – she had 7 at the time of her death- with fewer medications than she was taking when she entered the doctor’s office. My response to this is perhaps a bit extreme, but it was one employed by my healthy great grandmothers: take no pills! -Gail
Response:
- Hide quoted text — Show quoted text -<droz…@home.com
wrote in message news:38da72a7.5017620@news… On Thu, 23 Mar 2000 12:21:58 -0500, Robert Ames <am…@bellsouth.net wrote: . It does NOT mean that medication is being given unnecessarily, which is what you are implying. Not just implying, the article said: These data show that there is an excess of patients who are not in the normal range of thyroid function. Such patients may be at risk for organic consequences of overtreatment or undertreatment or (in the case of those with suppressed TSH levels) may be taking thyroid hormones for reasons other than replacement. Tell me what are these **necessary** reasons for taking thyroid hormones other than as replacement? Feeling good? Weight loss?
Or what the doctor teaching a course said about giving out thryoid medications is that they were used as "get out of my office" prescriptions. J – Hide quoted text — Show quoted text -
Kathryn droz…@home.com
Response:
"Joan Livingston" <joan.livingst…@gte.net
wrote in message
news:UYxC4.796$QJ3.170052@dfiatx1-snr1.gtei.net… – Hide quoted text — Show quoted text -
<droz…@home.com wrote in message news:38da72a7.5017620@news… On Thu, 23 Mar 2000 12:21:58 -0500, Robert Ames <am…@bellsouth.net wrote: . It does NOT mean that medication is being given unnecessarily, which is what you are implying. Not just implying, the article said: These data show that there is an excess of patients who are not in the normal range of thyroid function. Such patients may be at risk for organic consequences of overtreatment or undertreatment or (in the case of those with suppressed TSH levels) may be taking thyroid hormones for reasons other than replacement. Tell me what are these **necessary** reasons for taking thyroid hormones other than as replacement? Feeling good? Weight loss? Or what the doctor teaching a course said about giving out thryoid medications is that they were used as "get out of my office"
prescriptions.
J Kathryn droz…@home.com
If a doctor prescribes a drug, such as synthroid, as a *get out of my office*, or a *feel good* , medicine, that is malpractice. In my experience with doctors, they rarely want to prescribe anything, except antidepressants. The study only has the one sentence talking about taking thyroid medication for reasons other than replacement. It isn’t mentioned anywhere else. This is a study based on people filling out a questionnaire. Not the most reliable of studies. I would like to know for what other reasons someone would take thyroid. Other than…to feel good. I was disappointed that it didn’t mention other reasons. gs
Response:
"Eva D. Struction" <EvaDSt…@aol.com
wrote in message
news:QInC4.16697$iP.1163293@bgtnsc04-news.ops.worldnet.att.net…
Joan Livingston wrote in message … Uhhhh.. …………does one expect any other result from a study funded
by
Knoll Pharaceuticals – the makers of Synthroid? (Synthroid, the second largest selling drug in the US – supplemental thyroid medication) Check ‘em out on the web. ——— See, this is what I was just saying. *Any* time you see the word "undertreated," it’s a red flag. It tells you there is a very high likelihood a drug company is trying to snag new customers.
All I can say is my Mom died from undiagnosed thyroid problem. It is a very real health concern. Especially for older women. I think people should read studies, and then question their doctors. It is a very REAL problem. – Hide quoted text — Show quoted text -
Now this article particularly interests me because of my co-worker who’s taking Synthroid and has now been given Evista to prevent the Synthroid
from
giving her osteoporosis. I asked her why she was taking Synthroid in the first place, and she said she’d had no symptoms, but was put on it after a blood test showed she was mildly hypothyroid. She said the doctor told her that the thyroid gland "just deteriorates with age." (She was in her 40s at the time, is now
52.)
I asked her why she was given Evista rather than Fosamax, and she said "My doctor said Evista is better than Fosamax because it also lowers your bad cholesterol." When I asked her that question, I hadn’t read this article yet and didn’t realize that the Synthroid itself is supposed to be
lowering
her cholesterol. But I checked the PDR. I found that Evista increases the risk of ovarian cancer (in rats, no data on humans yet) and the risk of abnormal blood
clot
formation. Fosamax doesn’t have any such dangerous risks, although the
way
you have to *take* Fosamax is a big pain in the butt. I find this all very interesting. Eva
Sounds like your friend needs to get active in her healthcare. Symptoms of thyroid disease often go unnoticed because they are so symptoms of various other conditions….perimenopause and menopause for example. Maybe you should *encourage* your friend to question her doctor and the choice of medication. gs
Response:
I remembered the medical term for the type of coma , Myxedema Coma. Myxedema is severe hypothyroidism. FYI….my posts contain several spelling errors. Disregard them…thanks. gs .
Response:
On Thu, 23 Mar 2000 12:21:58 -0500, Robert Ames <am…@bellsouth.net
wrote:
. It does NOT mean that medication is being given unnecessarily, which is what you are implying.
Not just implying, the article said:
These data show that there is an excess of patients who are not in the normal range of thyroid function. Such patients may be at risk for organic consequences of overtreatment or undertreatment or (in the case of those with suppressed TSH levels) may be taking thyroid hormones for reasons other than replacement.
Tell me what are these **necessary** reasons for taking thyroid hormones other than as replacement? Feeling good? Weight loss? Kathryn droz…@home.com
Response:
Joan’s speculative scenario about drug-layering really rang a bell with me! At the time of my mother’s death from breast cancer last month she was taking 21 different medications (including synthroid, by the way…her thyroid had been destroyed by radiation about 11 years ago.) Her breast cancer had been diagnosed in 1972 and since then she was in and out of the hospital for chemo, radiation and reconstructive surgeries countless times. (Actually, I am going amuse myself by counting some of these things- creating a chronology of her trials…I just received all her medical records and her calendars back to the mid-70s.) Each surgery or treatment generated a host of auxillary drugs to deal with the myriad symptoms created by the treatment or surgery, increasing the drugs geometrically. She rarely left a doctor – she had 7 at the time of her death- with fewer medications than she was taking when she entered the doctor’s office. My response to this is perhaps a bit extreme, but it was one employed by my healthy great grandmothers: take no pills! -Gail
Response:
Uhhhh.. …………does one expect any other result from a study funded by Knoll Pharaceuticals – the makers of Synthroid? (Synthroid, the second largest selling drug in the US – supplemental thyroid medication) Check ‘em out on the web. J – Hide quoted text — Show quoted text -<droz…@home.com
wrote in message news:38d9b40c.37243615@news… On 23 Mar 2000 05:26:57 GMT, mpitc2…@aol.comnospam (MPitc2000) wrote: New Study Shows Twice as Many Americans May Suffer from Undiagnosed
Thyroid
Disease I don’t think that anyone on asm has ever said that undiagnosed thryroid disease was not a problem. Largest-Ever Prevalence Study Links Mildest Forms of Hypothyroidism to Increases in Cholesterol; Exposes Need for More Widespread Thyroid
Testing
DENVER, Feb. 27 /PRNewswire/ — The largest study to date evaluating the prevalence of thyroid disease indicates there may be more than 13 million Americans who are unaware they have a thyroid condition even though the
disease
may be impacting their short- and long-term health. For the original study article in the Feb 28 2000 Archives of Internal Medicine online see: http://archinte.ama-assn.org/issues/v160n4/full/ioi90027.html The Colorado Thyroid Disease Prevalence Study Gay J. Canaris [ et al ] [ small quote ] Results from this study also highlighted the large number of patients taking thyroid hormones who were not in the therapeutic range. Clinicians may therefore consider monitoring patients on thyroid replacement more frequently. 40% of those on thyroid medications in fact. Why?. Overtreatment could be one part of this and that is what all the commotion was about on asm recently. Kathryn droz…@home.com
Response:
New Study Shows Twice as Many Americans May Suffer from Undiagnosed Thyroid Disease Largest-Ever Prevalence Study Links Mildest Forms of Hypothyroidism to Increases in Cholesterol; Exposes Need for More Widespread Thyroid Testing DENVER, Feb. 27 /PRNewswire/ — The largest study to date evaluating the prevalence of thyroid disease indicates there may be more than 13 million Americans who are unaware they have a thyroid condition even though the disease may be impacting their short- and long-term health. This is double the previously suspected number of undiagnosed cases in the United States, according to data published in today’s Archives of Internal Medicine. The study also found that even the slightest decrease in thyroid function may increase cholesterol levels, possibly increasing a patient’s risk for cardiovascular disease. This link between the early stages of underactive thyroid ("subclinical" hypothyroidism) and cholesterol levels provides evidence that untreated patients may experience serious negative health consequences. As thyroid function declined, the study found, patients reported more symptoms. But, while there was a positive association between the proportion of symptoms reported and progressive thyroid failure, this distinction was not as clear as would have been expected. In addition, no one symptom was a clear indicator of thyroid failure. "The link between all stages of hypothyroidism and cardiovascular health, and the vague correlation between symptoms and disease state, points to the need for more widespread thyroid stimulating hormone (TSH) testing and more aggressive treatment, especially for subclinical patients," said E. Chester Ridgway, MD, head of the Division of Endocrinology at the University of Colorado Health Sciences Center. Study Findings The study was conducted to determine: the prevalence of abnormal thyroid function; the relationship between thyroid function and lipid levels; and the connection between thyroid failure and the presence of symptoms. Prevalence The study found that of the 25,862 participants, 11.7 percent had abnormal serum TSH levels. Evaluating incidence according to over- and underactive thyroid cases, 2,450 patients or 9.5 percent had an underactive thyroid (hypothyroidism) and 570 or 2.2 percent of the population had an overactive thyroid (hyperthyroidism). "Surprisingly, the prevalence of hypothyroidism was higher than expected," Dr. Ridgway said. "Based on previous data, we suspected five to ten percent of the population had a failing thyroid gland. But these results here showed that hypothyroid prevalence was on the higher end — closer to 10 percent." Among patients not taking thyroid medication, 8.9 percent were hypothyroid and 1.1 percent were hyperthyroid. This indicates 9.9 percent of the population had a thyroid abnormality that had most likely gone unrecognized. When extrapolated to account for national demographics, there may be 13 million Americans with an undiagnosed thyroid condition. The percentage of patients with hypothyroidism was greater for women for each decade of age after age 34. Thyroid Disease & Cholesterol A higher proportion of clinically hypothyroid patients had elevated total cholesterol levels as compared to those with normal thyroid function. While it has been known for decades that overt hypothyroidism contributes to elevated cholesterol levels, this is the largest study to show that the cholesterol levels among patients with mildly decreased thyroid function were significantly higher than the cholesterol levels in euthyroid patients. Average total cholesterol levels for patients with overt hypothyroidism were 251 mg/dL and the average total cholesterol levels for subclinical hypothyroid patients were 224 mg/dL — both above 200 mg/dL, the marker used to indicate elevated cholesterol levels that warrant medical attention. Because the connection between hypothyroidism and cholesterol is so clear, the National Cholesterol Education Program and the U.S. Food and Drug Administration recommend thyroid testing in patients with high cholesterol levels. "This study was novel in that it drew a clearer connection between mild or early stages of thyroid failure and its effect on cholesterol levels," Dr. Ridgway said. "It showed that as the thyroid gland fails and less thyroid hormone is produced, blood cholesterol levels rise. This has serious long-term consequences for the patient’s health particularly in the area of cardiovascular disease." Symptoms Scales as Indicators to Thyroid Disease Overt hypothyroid patients reported a greater percentage of symptoms than did the subclinically hypothyroid group. Both overt and subclinical patients reported more total symptoms than euthyroid individuals. But no one symptom was a predictor of thyroid failure. While there was an increase in the likelihood of thyroid disease as the number of reported symptoms increased, these symptoms are often vague and develop slowly so they go un-noticed. "Thyroid symptoms are so common and are often mistaken for signs of aging, menopause, depression or stress," said Gay Canaris, MD, assistant professor of internal medicine, University of Nebraska Medical Center. "Since we can’t rely upon reported symptoms alone to detect disease, we as physicians should be conducting more thyroid testing." Study Design This cross-sectional study evaluated the largest-ever patient population. Participants were solicited from the annual statewide health symposium in Colorado which provides testing for hypertension, colon cancer, glaucoma and skin cancer. In 1995, sensitive tests of thyroid function were added to the panel of blood analyses, and a questionnaire for hypothyroid symptoms was included with the survey. Demographics and thyroid function analyses for 25,862 patients, representing 111 sites, were quantified and reported in this study. The Thyroid Health Survey included a symptoms questionnaire that evaluated traditional thyroid symptoms and asked the patient to further identify each symptom as "current" (present at the time of the survey) or "changed" (symptom that emerged within the past year). A symptom index was calculated in the manner of Billewicz et al. The survey also included questions on personal history, family history and demographics. Serum TSH concentrations were measured by third-generation immunochemiluminescent assay. Normal range was a TSH level between 0.3 and 5.1 mIU/L, subclinical hypothyroidism was characterized by an elevated TSH level (greater than 5.1 mIU/L) and a normal T4, and overt hypothyroidism was evaluated as an elevated TSH level (greater than 10.0 mIU/L) and a decreased T4. The Critical Role of the Thyroid Gland The thyroid gland plays a vital role in overall body function during all stages of life. Although relatively small, it produces a hormone that influences every cell, tissue and organ in the body. The thyroid regulates the body’s metabolism — the rate at which the body produces energy from nutrients — and affects heart rate, energy and mood. If a person has normal thyroid function, they are considered to be euthyroid. When the thyroid gland is not working properly, it can become either underactive (resulting in hypothyridism) or overactive (resulting in hyperthyroidism). Signs and symptoms of an underactive thyroid include fatigue, depression, forgetfulness, unexplained weight gain, and menstrual irregularities. An overactive thyroid is marked by irritability/nervousness, sleep disturbances, unexplained weight loss, muscle weakness and vision problems. If left untreated, thyroid disease may lead to an increased risk for heart disease, osteoporosis and infertility. Thyroid disease can strike anyone at any time, but is more common in women. One woman in eight will develop a thyroid disorder during her lifetime. Incidence also increase with age — by age 60, more than 20 percent of American women will have a thyroid disorder. Thyroid disease can be diagnosed through a simple blood test called a TSH (third generation thyroid stimulating hormone). Once diagnosed, hypothyroidism can be treated with a synthetic hormone replacement tablet (levothyroxine sodium tablets, USP), taken once-a-day. SOURCE University of Colorado CO: University of Colorado ST: Colorado IN: HEA MTC SU: 02/27/2000 15:00 EST http://www.prnewswire.com
Response:
On 23 Mar 2000 05:26:57 GMT, mpitc2…@aol.comnospam (MPitc2000) wrote:
New Study Shows Twice as Many Americans May Suffer from Undiagnosed Thyroid Disease
I don’t think that anyone on asm has ever said that undiagnosed thryroid disease was not a problem.
Largest-Ever Prevalence Study Links Mildest Forms of Hypothyroidism to Increases in Cholesterol; Exposes Need for More Widespread Thyroid Testing DENVER, Feb. 27 /PRNewswire/ — The largest study to date evaluating the prevalence of thyroid disease indicates there may be more than 13 million Americans who are unaware they have a thyroid condition even though the disease may be impacting their short- and long-term health.
For the original study article in the Feb 28 2000 Archives of Internal Medicine online see: http://archinte.ama-assn.org/issues/v160n4/full/ioi90027.html
The Colorado Thyroid Disease Prevalence Study Gay J. Canaris [ et al ]
[ small quote ]
Results from this study also highlighted the large number of patients taking thyroid hormones who were not in the therapeutic range. Clinicians may therefore consider monitoring patients on thyroid replacement more frequently.
40% of those on thyroid medications in fact. Why?. Overtreatment could be one part of this and that is what all the commotion was about on asm recently. Kathryn droz…@home.com
Response: